In this episode of AudioHelicase, we sit down with three Whitehead Institute researchers driving breakthroughs in disease treatment. Join us as we explore some of the toughest challenges they’re overcoming to move transformative therapies from lab bench to your medicine cabinet.
Credits:
Interviews, production, and hosting by Shafaq Zia.
Music and sound effects:
Crescent Bloom by Kai Engel (CC BY-NC 4.0)
OBJPlls-INT_Pills Rattling by Alessia Pultrone (CC BY-NC 4.0)
Asthma Inhaler — Sprayed/ Dispensed 2 times by MutilatorBCB (CC0 1.0)
Velcro 7 by CassieTee (CC BY-NC 3.0)
Illustration: DrawImpacts
Whitehead Institute Member Siniša Hrvatin discusses his research on the neuroscience of hibernation.
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Making our world more sustainable to preserve it for future generations will take not just one but many solutions. Researchers at Whitehead Institute are exploring how the natural world could teach us how to improve the sustainability of how we produce food, how we make medicines, how we make products more durable, and potentially how … Continue reading AudioHelicase Special: How researchers at Whitehead Institute are building a more sustainable future →
In this episode of AudioHelicase Podcast, Whitehead Fellow Silvi Rouskin discusses her research on solving the structure of the novel coronavirus’s RNA genome, with the goal of revealing weak points in the virus’s gene regulation that new drugs could potentially target. Music: “Versailles” by Pierce Murphy (CC-BY 4.0). Produced by Conor Gearin.
On this episode of AudioHelicase podcast, Whitehead Fellow Olivia Corradin talked about investigating the genetic underpinnings of diseases through a new technique she developed, the outside variant approach. Applying the method to study the autoimmune disease multiple sclerosis (MS), Corradin and colleagues identified a role for a cell type in the brain in MS, offering … Continue reading Whitehead Institute’s Olivia Corradin on a New Way to Probe Disease Genetics →
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In this special episode of AudioHelicase podcast, we’re taking a look at how our researchers are identifying the key players that help conduct the cell’s symphony — the proteins and molecules that direct many other parts of the cell on when and how to do their jobs. The episode features highlights from interviews with Whitehead … Continue reading AudioHelicase Special: The Conductors of the Cell’s Symphony →
In this episode of AudioHelicase, Whitehead Institute Member Pulin Li talks about how her lab engineers cells in Petri dishes to communicate with each other and form patterns, recreating processes seen in embryo development—and how this work could eventually inform efforts to grow tissues in the lab. Produced by Conor Gearin Music: Pierce Murphy, … Continue reading Whitehead Institute’s Pulin Li on creating multicellular patterns in a Petri dish →
In this episode of AudioHelicase, Whitehead Institute Member Ankur Jain discusses how RNA can clump in cells and the diseases, such as Huntington’s and amyotrophic lateral sclerosis (ALS), that are associated with these aggregations.
In this episode of AudioHelicase, Whitehead Institute Member Iain Cheeseman discusses how his work on the kinetochore provides a window into cell division and what happens when this vital cellular function goes awry.